Named after Lake Mburo, the park occupies total space of 370 km² with wetland habitats that constitute 20% of the park. In 1993, the park graduated from a mere reserve to a full national park. L. Mburo National is one the most accessible parks from Kampala or Entebbe; it lies center of an extensive rich acacia woodland. The vegetation is a mélange of bushy thickets, open and wooded savannas to dense forests. The elevation ranges between 1,220 m – 1,828m above sea level.

Home to a diversity of wildlife, L. Mburo is home to 68 mammal species including Burchell’s Zebras, Eland (largest antelope), Topis, and Impalas; L. Mburo is the only park with Impalas in Uganda. On the list of residents, L. Mburo also has warthogs, buffaloes, oribi, defassa, waterbucks, and reedbucks. Among predators are leopards, hyenas, and a recent return of lions after decades of extinction.  Semi-aquatics like hippos and crocodiles reign in the waters of the five lakes within the park. The swampy provinces within the park harbor papyrus residents like sitatunga antelopes and the papyrus gonolek.

Small as it is, L. Mbruro National Park is home to over 332 bird species including the rare Shoe-bill stork, papyrus yellow warbler, African finfoot, saddle-billed stork, brown-chested wattled plover, Carruthers Cisticola, Tabora Cisticola, great snipe, Abyssinian ground hornbill and the white-winged warbler among others.

Lying in the middle of two great physical features; Lake Victoria and the Rwenzori Mountains, L. Mburo receives an average rainfall of 800mm annually. Situated along the equator, the climate is typically tropical and rainfall is quite unpredictable but heavy rains are experienced in April and November. Records have it that the average temperature s 27.5 Centigrade.

Attractions and activities include game-drives, safari walks in Rwonyo areas, boat-rides on L. Mburo and bird-watching among others.